Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice
نویسندگان
چکیده
منابع مشابه
Spontaneous Intracerebral Hemorrhage: Management
Spontaneous non-traumatic intracerebral hemorrhage (ICH) remains a significant cause of mortality and morbidity throughout the world. To improve the devastating course of ICH, various clinical trials for medical and surgical interventions have been conducted in the last 10 years. Recent large-scale clinical trials have reported that early intensive blood pressure reduction can be a safe and fea...
متن کاملSpontaneous intracerebral hemorrhage during acute and chronic hypertension in mice.
Oxidative stress and matrix metalloproteinases (MMPs) contribute to hemorrhagic transformation after ischemic stroke and brain injury after intracerebral hemorrhage (ICH). The goal of this study was to develop a new model of spontaneous ICH, based on the hypothesis that acute, superimposed on chronic, hypertension produces ICH. We hypothesized that increases in angiotensin II (AngII)-mediated o...
متن کاملManagement of Spontaneous Intracerebral Hemorrhage
PURPOSE OF REVIEW We review the current evidence for medical and surgical treatments of spontaneous intracerebral hemorrhage (ICH). RECENT FINDINGS Therapy with hemostatic agents (e.g. factor VIIa and tranexamic acid) if started early after bleeding onset may reduce hematoma expansion, but their clinical effectiveness has not been shown. Rapid anticoagulation reversal with prothrombin concent...
متن کاملSeizures after Spontaneous Intracerebral Hemorrhage
OBJECTIVE In patients with spontaneous intracerebral hemorrhage (ICH), the risk factors for seizure and the effect of prophylactic anticonvulsants are not well known. This study aimed to determine the risk factor for seizures and the role for prophylactic anticonvulsants after spontaneous ICH. METHODS Between 2005 and 2010, 263 consecutive patients with spontaneous ICH were retrospectively as...
متن کاملPredictive Factors for ICU Admission in Patients with Spontaneous, Nontraumatic Intracerebral Hemorrhage
Background and purpose: Non-traumatic or spontaneous supratentorial hemorrhage (ICH) is a condition that may be difficult to diagnose and treat. In this study, we decided to determine certain criteria for hospitalization of patients with non-traumatic supratentorial ICH in Intensive Care Unit (ICU) . Materials and methods: This cross-sectional study was performed in Mashhad Ghaem Hospital ...
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ژورنال
عنوان ژورنال: Journal of Visualized Experiments
سال: 2011
ISSN: 1940-087X
DOI: 10.3791/2618